Beat gum disease with a cuppa

Now you know how fond I am of green tea, and actually I have found a new one in my supermarket made by Dr Stuart which combines green tea and rice. Sounds disgusting but actually it sweetens the green tea, and makes it more palatable and as I have just found another good reason for drinking it, I encourage you to try it. A cup of green tea per day may help keep gum disease at bay, a new study suggests.

A report in the Journal of Periodontology says that researchers at Kyushu University in Fukuoka, Japan found that among middle-aged Japanese men, the odds of having gum disease declined as their intake of green tea went up. For each daily cup they drank, the risk of having signs of gum disease – including receding, easily bleeding gums – went down and this may be because green tea has a high concentration of antioxidant compounds called polyphenols. Much gum disease arises from bacterial infection, and lab research suggests that green tea polyphenols can inhibit those germs and the damage they cause. It is of course no substitute for good oral hygiene and the dentist, but prevention is always better than cure – particularly when green tea has so many other health benefits as well.

New evidence of infection link to childhood Leukaemia

Every 20 minutes someone in the UK is diagnosed with cancers of the blood such as leukaemia, lymphoma and myeloma. UK researchers have for the first time identified the molecule that stimulates leukaemia to develop in children, according to a study published in the April edition of the Journal of Clinical Investigation.

Scientists at The Institute of Cancer Research have observed that pre-leukaemic stem cells multiplied substantially at the expense of normal cells when exposed to a molecule produced in the body called TGF.

TGF is triggered as a normal response by the body to infection and so the new finding provides the first experimental evidence as to how common infections might trigger childhood leukaemia.

“We had already identified that a genetic mutation occurring in the womb created these pre-leukaemic cells,” Dr Anthony Ford from The Institute of Cancer Research (ICR) says. “But we have been looking for a trigger that could send these cells down the pathway to leukaemia. We believe TGF is part of that missing link.”

In a study of identical twin girls last year, ICR scientists discovered a genetic mutation – the fusion of the TEL (ETV6) and AML1 (RUNX1) genes – was responsible for initiating childhood acute lymphoblastic leukaemia in the womb.

This mutation means pre-leukaemic cells grow in the bone marrow as a silent time bomb that can stay in the body for up to 15 years, but requires other factors to convert into leukaemia. Evidence suggests the mutation may be present in as many as one in 100 babies,but only about one in 100 of those children with the mutation then go on to develop leukaemia.

The latest ICR study, funded by Leukaemia Research, found TGF creates conditions that allow the pre-leukaemic cells to multiply. This increases the chance that some will become even further damaged in a way that results in the child developing leukaemia. Before this study, there had been only circumstantial evidence to implicate infections in the progression from a child carrying pre-leukaemic cells to actually having leukaemia. There was no evidence of the mechanism by which this might happen. While infection is clearly only one factor in triggering progression, this study greatly increases the strength of evidence for its role in the commonest form of childhood leukaemia.

It also gives hope for the development of more effective early diagnosis and treatment for childhood leukaemia.

How your body clock affects how you age

We all have an internal body clock, or circadian rhythm that dictates whether we are an owl or a lark and governs many of our normal functions such as body temperature, brain activity, hormone production and metabolism. These things are well known and we can study our own rhythms to help us balance our lives better so we don’t study at a time when our body is not at its mental best, or try to sleep when it is naturally ready to go out and party.

Now it also appears to affect how we age, at least according to new research from Washington University School of Medicine in St. Louis who have discovered that our inner biological clock actually communicates directly with the processes that govern aging and metabolism.

As we age, our circadian rhythm declines and the researchers believe that this could be a contributing factor to age-related disorders such as type 2 diabetes and is linked to a gene called SIRT1 which at the center of a network that regulates aging, coordinates metabolic reactions throughout the body and manages the body’s response to nutrition. This biochemical mechanism can directly drive the oscillation of the body’s daily clock and is potentially a way to correct metabolic disorders and improve health as people age.

Natural help to heal scars

As someone who has been naturally careless since childhood, I have obtained a number of small scars, not least from my propensity to iron over my hands instead of the garment and despite the longest oven gloves on the planet I can still manage to burn myself getting things out of the oven, so I have investigated natural remedies for some time. Recently I was talking to a client and the subject came up, and as I passed on what had worked for me I realized it might also be helpful for you too – so here goes.

Obviously scars will heal and diminish over time, but you can take action by using the following natural remedies to minimize them:

ACE is the combination nutrition supplement you need first, as vitamin A is essential to maintain healthy skin, collagen is vital for your skin and comes from an adequate supply of vitamin C, and to reduce inflammation and reduce your risk of scarring you can’t do better than vitamin E. Some people take this as a separate supplement and squeeze the oil out directly onto the skin.

Raw, organic honey – such as Manuka – applied directly to the skin will moisturise and its antibacterial qualities help heal scarring.

If you have an aloe vera plant you can cut the tip of a leaf and smooth the liquid gel directly onto cuts and burns to soothe and minimise scarring.

Herbal help comes from lavender oil and comfrey to promote healing and comfrey to help stop scar tissue forming.

Why a bump on the head is never trivial

I am indebted to Dr Ben Kim for the following information, as it serves as a timely reminder never to shrug off any injury to the head as trivial and to alert you to what to look out for. It has been prompted by the death of the actress Natasha Richardson, on the 18th of March from what initially seemed like a minor bump when on a nursery ski slope in Quebec. She laughed off the incident, felt fine with no symptoms, and refused any medical treatment, but that minor blow to her head had caused internal bleeding which formed a clot (an epidural haematoma) which in turn placed pressure on her brain and within a short period of time caused her death.

Along the sides of your head in the area around your temples, your epidural space houses an artery called your middle meningeal artery, whose job is to provide steady blood supply to your meninges. The portion of skull that protects this area is quite thin and weak compared to the rest of your skull which is why even a low force blow to this area could lead to a fracture and tearing of your middle meningeal artery. If this happens then blood can quickly begin to pool in your epidural space and because your heart would continue to send blood to the area, and this blood wouldn’t be drained by your veins, the result is increased pressure on your brain tissues, which could lead to death of brain cells from oxygen deprivation.

What to look out for: A fall, a casual blow to the head, that may seem unimportant can be fatal and it always pays to be checked out. About 50% of people who experience epidural hematomas briefly lose consciousness, but appear to be just fine when they come to. If pressure in the head continues to build, then over a period of just a few hours, a searing headache tends to develop as increased intracranial pressure causes the dura mater to tear away from the skull. Other signs and symptoms that may develop include:

* Lethargy
* Nausea
* Dizziness
* Drowsiness
* Weakness on one side of the body

Vigilance is the only safeguard; you need to be carefully monitored after any blow to the head and be prepared to seek immediate medical help. However fine you feel, don’t ignore it.

Lack of vitamin D weakens young girls’ muscles

Another reason not to neglect eggs, particularly for teenage girls, is that new research in the USA and Germany has found that having insufficient vitamin D may cause weaker muscles.

A lack of the vitamin causes problems with calcium absorption, and can lead to bone weakness, fractures and osteoporosis as well as increasing the risk of cancer, heart disease and autoimmune disorders. Certainly it is known to impact our muscular and skeletal system and cause weakness, but what’s news it that it can also affect muscle power and force. The researchers tested their theory on nearly 100 girls between 12 and 14 at inner city schools and found that overall 75 percent of them had less than ideal levels of vitamin D, but were not showing any symptoms related to deficiency.

The girls were put through a variety of sport exercises, mainly involving jumping, and it was found that there was a direct correlation between vitamin D blood levels and the girls’ performance on the muscle strength tests. Recent studies suggest that as many as 55 percent of apparently healthy U.S. adolescents might be vitamin D deficient and so it would be worth making sure that girls include the best sources every day such as oily fish, eggs and fortified foods like breakfast cereals and powdered milk. Plus that basic, free source good old fashioned sunlight.

Fried eggs can benefit cholesterol!

You can’t entirely blame Edwina Currie, though anyone who writes as badly as she does ought to be blamed for something, but we have steadily been eating fewer and fewer eggs. The dreaded phrase ‘high in cholesterol’ have sealed their fate, but ironically it now seems that new research shows they could actually reduce a risk factor for heart disease.

We have been warned over and over again about the dangers of eggs producing cholesterol that will clog up your arteries – though as cholesterol is essential to our health and wellbeing it has always been a mixed message.

The main target has been those people who have high blood pressure, and instead of a natural regime of exercise and diet many doctors have been prescribing an Angiotensin- Converting Enzyme (ACE) inhibitor drug. How about a couple of fried eggs instead? Two splendid Canadian researchers at the University of Alberta recently ran lab tests to see whether eating fried eggs or boiled eggs would produce greater amounts of ACE inhibitory peptides and the fried eggs were the winners!

They found that cooked eggs could generate a number of potent ACE inhibitory peptides and although I am not advocating you have them every day, do not remove them from your diet because of the cholesterol scare but eat in moderation – as you should do with all things in your diet.

Incidentally, the research that led to the egg/cholesterol scare was done on powdered eggs and the problem has always been cholesterol that has been heated and exposed to air for an extended period. This does not occur with ‘real’ eggs as the yolk sac insulates the cholesterol from oxidation. Many doctors believe that there is no link between eggs and having high cholesterol levels and in fact if you don’t have enough cholesterol from food sources then your body is forced to manufacture it as it is essential for your health. This form of cholesterol that the body produces is more likely to be deposited in blood vessel walls than any form of cholesterol found in eggs.

Egg and chips anyone?

New hope for infertility treatment

It has just been reported in the Society for Endocrinology journal that the hormone kisspeptin shows promise as a potential new treatment for infertility. Research carried out at Imperial College London, have shown that giving kisspeptin to women with infertility can activate the release of sex hormones which control the menstrual cycle. For women with low sex hormone levels this could be a breakthrough for a new fertility therapy. Kisspeptin sounds like a loving form of antacid, but is actually a product of the KISS-1 gene and a key regulator of reproductive function. If we do not have this then gene, then puberty does not occur and we do not achieve sexual maturity.

The research was primarily concerned with a small group of ten women whose periods had stopped due to a hormone imbalance and who were injected with either kisspeptin or saline as a control measure. All the women gave blood samples to measure their levels of the two sex hormones essential for ovulation and fertility: luteinising hormone (LH) and follicle stimulating hormone (FSH).

The group who were given the kisspeptin showed to a 48-fold increase in LH and a 16-fold increase in FSH, when compared to the control group who were given only saline. The lead researcher, Dr Waljit Dhillo, said that this discovery offers huge promise as a treatment for infertility as it suggests that kisspeptin treatment could restore reproductive function in women with low sex hormone levels.

Oxygen therapy showing hope for autistic children

Many studies have suggested treatment that might help autistic children but the majority of them are anecdotal and not generally provable or applicable. Each child is different, but a new oxygen therapy has been put through a controlled trial and is reporting definite clinical improvements.

Six centres in the US that specialise in treating autistic children have been running a controlled trial on 62 children aged from two to seven. They have been using something they call hyperbaric therapy which involves the child being put into a pressurized chamber and then breathing in pure oxygen.

The children were divided randomly into two groups; one who got 40 hours of treatment in the chamber with an atmospheric pressure of 1.3 atm and the second group who had a much less pressured chamber and a lower dose of oxygen. Changes in their behaviour were monitored using three different criteria; the Clinical Global Impression (CGI) scale, the Aberrant Behavior Checklist (ABC), and the Autism Treatment Evaluation Checklist (ATEC).

Those children who had the treatment level of oxygen and pressure were found to have experienced significant benefits in terms of their overall functioning, eye contact, and social interaction when compared to the children in the non-treatment group.

As this is the first control study to be reported, it is worth investigating whether similar treatment is available in the UK. If your doctor or specialist wishes further information this report appeared in MLA BMC Pediatrics (2009, March 16). As Hyperbaric Treatment For Autism Reports Significant Clinical Improvements.

Yet another difference between men and women

Well apart from the obvious ones we all know about; that men need more of the duvet and don’t eat as much as chocolate, it seems our aspirin response is different too. A daily aspirin for those men over 45 and women over 55 is often recommended as a preventive for heart attacks, but it seems that the benefit differs by gender.

Men do get fewer heart attacks with a daily dose, but it doesn’t affect women in the same way. Their benefit lies in the fact it reduces the risk of stroke, not of heart attacks.

New research published this month in the Annals of Internal Medicine has also focused on the possible dangers of regular aspirin use in causing gastrointestinal bleeding. This risk gets higher as the dose increases and the new recommendation is that no more than 75mg a day is just as effective as higher amounts. If you already have heart disease then taking 100mg or more of aspirin a day will not be of any benefit for the existing condition.

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